A V Foundation SPORE Clinical Trial Supplement Grant Awarded To The University of Pittsburgh Cancer Institute

 The V Foundation for Cancer Research, one of the nation’s leading cancer research fundraising organizations, announced that a Supplement to the Lung Cancer Specialized Program of Research Excellence (SPORE) grant to support innovative clinical trials was recently awarded to Dr. Jill M. Siegfried at the University of Pittsburgh Cancer Institute. The $1 million grant was given in honor of Emily Miner, a 39 year old mother of two who was diagnosed with Stage 4 lung cancer.  Miner received the grant in her honor at the 2009 V Foundation Wine Celebration.

“Some of the most promising translational research is supported by the SPOREs, but there are never sufficient funds from NCI to launch the clinical trials which bring these new drugs and approaches to cancer patients. The V Foundation is meeting that need,” said Dr.  Robert Bast, chair of the Scientific Advisory Committee which reviewed the applications for this award.

The V Foundation SPORE Clinical Trial Supplement is awarded to individuals who promote interdisciplinary research and move basic research findings from the laboratory to clinical settings, involving both cancer patients and populations at risk of cancer. Dr. Siegfried will use the grant to help support the establishment of new clinical trials for lung cancer patients at University of Pittsburgh Medical Center’s Cancer Centers.

Dr. Siegfried’s research which found that estrogen acts as a proliferation agent in the lung, activating lung cancer development through pathways similar to those in breast cancer. Her research also demonstrates that it might be possible to inhibit lung cancer tumor growth with anti-estrogens.

Lung cancer is the deadliest type of cancer for both men and women worldwide.  More people die of lung cancer each year than of breast, colon and prostate cancer combined.  Unfortunately, because symptoms don’t appear in most patients until the disease is advanced, very few patients survive beyond five years.

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About The V Foundation for Cancer Research

The V Foundation for Cancer Researchwas founded in 1993 by ESPN and the late Jim Valvano, legendary North Carolina State basketball coach and ESPN commentator. Since 1993, The Foundation has raised more than $90 million to fund cancer research grants nationwide. It awards 100 percent of all new direct cash donations and net proceeds of events directly to cancer research and related programs. The Foundation, which has received seven consecutive top 4-star ratings from Charity Navigator, awards grants through a competitive awards process strictly supervised by a Scientific Advisory Board. For more information on The V Foundation or to make a donation, please visit