Funded by the Dick Vitale Pediatric Cancer Research Fund
Leukemia in babies and young children is a serious cancer, and there are few good treatments. A new drug that blocks a protein that helps leukemia grow is now being tested in clinical trials. Our team has a cancer researcher and a leukemia doctor. We will work together to learn why some leukemia cells do not respond to the drug. We will study leukemia cells and the cells around them to learn how they help leukemia live and grow. We will use a new mouse model to see how the drug affects leukemia and nearby cells. We will also test drug combinations to find ways to kill more leukemia cells while causing less harm to normal cells. Our goal is to find safer and better treatments for babies and young children with leukemia, who now have few good treatment options.
Location: University of Colorado Cancer Center - Aurora
Proposal: Bedside to Bench Discovery to Enhance the Reach of Menin Inhibitors in Pediatric ALL