The V Foundation for Cancer Research Chicago Epicurean Raises Over $1.13 Million for Cancer Research
Read moreState: North Carolina
Jessica Fu, M.D.
Funded by the Junior Jimmy V Celebrity Golf Classic
Paola Gehrig, M.D.
Funded by the Jimmy V Women’s Basketball Classic
Carolyn Sartor, M.D.
Funded by the Jimmy V Women’s Basketball Classic
Christopher Counter, Ph.D.
Andrew Futreal, Ph.D.
Andrew Krivoshik, M.D., Ph.D.
Funded by the Jimmy V Celebrity Junior Golf Classic
The Jim Valvano Post-Doctoral Fellowship
in Pediatric Cancer Research
Victoria Seewaldt, M.D.
Funded by the Jimmy V Women’s Basketball Classic
Gerold Bepler, M.D., Ph.D.
Corinne Linardic, M.D., Ph.D.
Funded by the Apple Gold Group
Rhabdomyosarcoma (RMS) is the most common soft tissue cancer of childhood. Because RMS has features of skeletal muscle, we and others have been trying to understand how muscle development pathways inside the tumor cells have gone awry. This project will study the role of a protein called SFRP3, which although it takes part in normal muscle formation, is co-opted to support RMS tumor formation. We aim to understand in more detail how SFRP3 works in RMS, and how to block it. Our goal is to someday use SFRP3 blockade as a therapeutic intervention.
