Madeline Hayes, PhD

Funded by the Dick Vitale Pediatric Cancer Research Fund

Neuroblastoma (NB) is a type of childhood cancer that is difficult to treat after it has spread throughout the body. Using animals that develop aggressive NB, we found different types of tumor cells that may lead to cancer spread. We are proposing to look very closely at these different tumor cells and determine how they may lead to NB spread and drug resistance in patients. We will also test new targeted drugs for their effects on NB spread and through our studies, new ways to treat aggressive childhood cancer may be found.

Location: Garron Family Cancer Centre at SickKids in Toronto - Toronto
Proposal: In vivo Characterization of Cell State Transitions Associated with DNA Damage Response Deficiency in Metastatic Neuroblastoma
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