Through these studies we hope to identify the transcription factors critical for the transformation of human breast cells, and to develop specific inhibitors of these transcription factors. Such transcription factor inhibitors may be novel therapeutic agents for the prevention and treatment of breast cancer.
Powel Brown, M.D., Ph.D.
Location: Cancer Therapy & Research CenterUniversity of Texas Health Science Center - Texas
Proposal: Role of the AP-1 transcription factor in regulating breast cell growth, invasion, and transformation
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