Co-funded by the Dick Vitale Pediatric Cancer Research Fund and the Jeff Gordon Children’s Foundation
Neuroblastoma is a childhood cancer that can be difficult to treat. Currently, studies are needed to figure out effective and safe ways to treat this type of cancer. Using animal models who can develop neuroblastoma, we found a special type of cells present within the tumors that allow them to grow and spread to other parts of body. By creating our own version of these cells, we can reverse their role and block the growth of tumors instead. We are proposing to use these modified cells to inhibit tumor growth. We will perform further modification on these cells to increase their success on killing cancer cells with less or no off-target effect on normal cells in the body. Through these studies, a new way to treat this childhood cancer may be found.