Jonathan W. Simons, M.D. 

President, Chief Executive Officer David H. Koch Chair
The Prostate Cancer Foundation

Dr. Jonathan W. Simons is the President, Chief Executive Officer, and David H. Koch Chair of the Prostate Cancer Foundation, Simons’ laboratories at Johns Hopkins University and Emory University made original contributions to prostate cancer immunotherapy and Immunobiology after inventing GM-CSF genetically-engineered vaccines for prostate cancer. Young physician-scientists in the Simons’ laboratories made original discoveries on the roles of interleukin-6, endothelin-1 and HIF-1alpha genes in the molecular biology of human prostate cancer bone metastasis. Dr. Simons is the Founding Director of the Winship Cancer Institute at Emory University in Atlanta and the Co-Director of the National Cancer Institute Center for Cancer Nanotechnology Excellence at Emory University and Georgia Tech. At Emory University, Dr. Simons was also Chief of Hematology and Oncology, Distinguished Professor of Hematology and Oncology at the Emory University School of Medicine and Professor of Material Sciences at the Georgia Institutes of Technology. Prior to recruitment to start the Cancer Institute at Emory University in 2000, Dr. Simons was Director of the Molecular Pharmacology Program and Gene Therapy Laboratory at the Johns Hopkins University School of Medicine, where he was an Associate Professor of Oncology and Urology.

Dr. Simons received his bachelor’s degree from Princeton University and his Doctor of Medicine degree from the Johns Hopkins University School of Medicine. He was a Rotary International Postgraduate Fellow in Humanities at the University of Kent, Canterbury, England, and a Nuffield Foundation Fellow in the Department of Biochemistry, University of Cambridge. Dr. Simons completed his residency in internal medicine at the Massachusetts General Hospital, Harvard Medical School, then began his career in cancer research as a Clinical Fellow in Medical Oncology and Postdoctoral Fellow in the Laboratory of Molecular Genetics at The Johns Hopkins Oncology Center under Dr. Bert Vogelstein.

Dr. Simons served in numerous board and leadership roles for the American Cancer Society, the American Association of Cancer Research, American Society of Clinical Oncology, American Urological Association, Congressionally Directed Medical Research Program, National Cancer Institute, Department of Defense, FasterCures and the Melanoma Research Alliance.